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1) CBD promotes drug-drug interactions (DDI) and potentiates the effects of numerous medications (5–10 M).
(2) CBD is a membrane interactor: it influences ion channels in various ways, including membrane pressure and direct binding (0.1–5 M).
(3) CBD has a powerful “meaning impact,” which means people expect it to function.
(4) According to some findings, CBD is 6 per cent orally bioavailable.
(5) The normal dose of CBD in nonmedicinal products is substantially lower than in clinical trials and prescriptions (25 mg in a typical nonmedicinal product versus 150–1500 mg/day in clinical trials).
(6) “CBD has the potential to be harmful to your health” (similar to other drugs).
(7) CBD can be chemically transformed to THC, but it does not appear to convert to THC in physiological settings (vide infra).
(8) CBD is now classified as an illegal supplement (“Adding CBD to food or marketing it as a dietary supplement is currently banned”).
(9) “CBD” is a common product label. Still, it is often deceptive: “CBD” products often include a slew of additional chemically complex substances in addition to fluctuating, often insignificant levels of CBD. Rather than blanket statements like “pure” or “natural,” valid CBD label claims require comprehensive analytical characterisation of its identity, purity, and stability.
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